Welcome to the training programme dedicated to mitochondrial research:
Quality Control of the Mitochondrial Gene Expression System in Health and Disease
MITGEST
MITGEST is a Doctoral Network (DN) funded within the framework of the Marie Skłodowska-Curie Actions (MSCA) and coordinated by the International Institute of Molecular Mechanisms and Machines of the Polish Academy of Sciences (IMol). MITGEST brings together world-class academic experts in mitochondrial DNA (mtDNA) maintenance and expression with leading private sector specialists in nucleic acid chemistry and the development of mitochondrial therapies. Our integrated approach aims to lead the way in understanding and treatment of mitochondrial diseases through cutting-edge research and innovation. Read more about MITGEST research
Our team of 11 doctoral candidates (DCs) will:
- Investigate how mitochondrial DNA (mtDNA) is maintained and expressed.
- Develop new methods to analyse RNA and DNA metabolism in mitochondria.
- Follow complex scientific and non-scientific training.
Why MITGEST is important?
Mitochondrial dysfunction is a key feature of many rare genetic disorders known as mitochondrial diseases. These chronic, often fatal conditions occur when mitochondria fail to produce enough energy for the body. Through research, MITGEST seeks to deepen our understanding of mitochondrial gene expression and develop new methods to treat a wide range of mitochondrial disorders. By advancing this research, MITGEST supports and enhances innovative treatment strategies and experimental medicine studies aimed at reducing mitochondrial dysfunction in various human diseases.
Learn more from our news articles
Have you met Mitola and Sam yet? If not, you need to read the latest comic book created by MITGEST, titled Mitola and the Mito-verse,...
MITGETS Doctoral Candidates share the recent publications Mitochondria are vital organelles present in almost all eukaryotic cells and are involved in the primary cellular metabolic...
World Mitochondrial Disease Awareness Week, observed from 16-22 September, is an annual campaign to raise awareness of mitochondrial diseases—rare genetic disorders that severely affect the...
MITGEST is excited to announce its upcoming second Training Week from 22-30 July 2024 in Nijmegen, Netherlands. Hosted by the Radboud Center for Mitochondrial Medicine,...
One of our doctoral candidates within the MITGEST doctoral network, recently undertook a three-month secondment at Goethe University Frankfurt. Under the esteemed guidance of Dr....
One of our doctoral candidates within the MITGEST doctoral network, recently undertook a three-month secondment at Goethe University Frankfurt. Under the esteemed guidance of Dr....
From 19 to 23 May 2024, the picturesque town of Jozefow, Poland, hosted an exceptional scientific gathering: the EMBO workshop on Molecular Biology of Mitochondrial...
Unlocking Biological Insights: Doctoral Candidate (DC3) Completes training on RNA-sequencing and Functional Interpretation Our Doctoral Candidate (DC3), Dory Vergallo has recently completed the esteemed course,...
APOE4 and Alzheimer’s – research background Alzheimer’s disease (AD), a debilitating neurodegenerative disorder, affects approximately 10% of people over the age of 65 worldwide. The...
One of our doctoral candidates within the MITGEST doctoral network, recently undertook a three-month secondment at Goethe University Frankfurt. Under the esteemed guidance of Dr....